Founders and Executives



Mervyn Maze

  • Tenured professor at UCSF, with endowed chair
  • Discovered, patented, & helped market Dexmedetomidine (Precedex®), Abbott/Hospira
  • Formed AlphaRx with Nobel Laureates Brian Kobilka & Michael Levitt
  • Co-discoverer of neuroprotective properties of Xenon
  • Previous Anesthesia Appointments: UCSF – Chair, Imperial College of London – Chair/Head of Division, Stanford University – Vice-Chair
  • Widely published and recipient of eponymous lectureships, international awards – Fellowships for excellence in preclinical & translational research (including work on Xe)



Prof. Nick Franks

  • Professor of Biophysics & Anaesthetics, Imperial College of London
  • Co-discoverer of neuroprotective properties of Xenon (patent filer)
  • World-renowned basic scientist widely published and recipient of international awards



  Bill Burns

  • Serial Health Care entrepreneur
    • Four new chemical entities
    • > 100 new medical devices
    • >$10B in revenue
  • Past President R&D and Anesthesia Laureate – Piramal Care
  • Founder/CEO – Minrad (AMEX:BUF) in 1996
  • Founder/CEO – Matrx Medical, largest manufacturer/distributor of emergency medical products in North America


Matt Napoletano

  • Pharmaceutical Executive with 20 years experience
  • Strategic portfolio development & in-line commercialization of branded products
  • Commercial positions of increasing importance with Insys, Cephalon (Teva) and Berlex Labs (Schering AG / Bayer)


World Class SAB providing expert guidance in core areas


Prof. Alex Evers

  • Physician-Scientist, Intensivist and Chair of Anesthesia at Washington University.
  • Reported on the harmful effects of anesthetics in neonatal models and the protection provided by xenon



Prof. Nick Franks
Scientific Advisory Board Chair

  • NeuroproteXeon Founder and Director
  • Biophysicist and filer of use patents of xenon for neuroprotection
  • Head of Biophysics, Imperial College London
  • World-renowned basic scientist with international awards



Mervyn Maze, MB ChB
NeuroproteXeon Founder and Director



Prof. Lena Sun
Pediatric Anesthesiologist
Emanuel M. Papper Professor of Pediatric Anesthesiology, Columbia University

Vice Chair, Department of Anesthesiology
Program Director, Pediatric Fellowship Training Program
Chief, Division of Pediatric Anesthesiology

  • Principal Investigator, Pediatric Anesthesia and Neuro-Development Assessment (PANDA) trial that addresses long-term effect of anesthesia on cognition in children
  • Member of numerous Pediatric Anesthesia Boards/Committees, and the organizer of international symposium on Pediatric Cardiovascular Medicine
  • Widely published, reviewer of multiple journals



Prof. Warren Zapol
Professor of Anaesthesia, Harvard Medical School; Reginald Jenney Professor of Anaesthesia
Harvard Medical School; Director, Anesthesia Center for Critical Care Research, MGH

  • Focus on the physiological and pathophysiological roles of nitric oxide (NO).
  • Pioneering studies on inhaled NO (INO) resulted in the treatment of ~30,000 patients per year in the US to vasodilate the pulmonary circulation and augment arterial oxygenation (hypoxic infants, hypoxic respiratory failure – especially after heart surgery).
  • Focus on the storage lesion of aged blood cells, and methods for preventing the toxic effects of extracellular hemoglobin that is released by hemolysis in malaria or genetic diseases such as sickle cell anemia.
  • Studying how to make the transfusion of heme-based oxygen carriers both safe and effective for transfusion in the field.
  • Widely published and recipient of international awards